KLOW Blend
KLOW Blend (GHK-Cu / BPC-157 / TB-500 / KPV multi-peptide research blend) · ≥98% (HPLC)
Multi-peptide reference blend (GHK-Cu, BPC-157, TB-500, KPV) characterized for in-vitro study of cytoprotection- and matrix-associated signaling pathways. For research use only.
- Why researchers study it
- Studied in vitro as a defined four-component reference material for investigating overlapping copper-tripeptide, gastric-derived pentadecapeptide, actin-binding fragment, and alpha-MSH-derived tripeptide signaling within a single analytical sample.
- Mechanism themes in research
- Copper-tripeptide coordination chemistry (GHK-Cu)Actin-binding / cytoskeletal sequestration motifs (TB-500)Melanocortin-derived anti-inflammatory signaling (KPV)Extracellular-matrix and cytoprotection-associated pathway literature (BPC-157)
- What the evidence does not establish
- Published references are in-vitro or pre-clinical and describe research context only. They do not establish safety, efficacy, or any outcome in humans or animals, and Helix makes no such claims.
- Quality markers
- ≥98% (HPLC)MS identityLot COACold-chain
KLOW Blend is a research-use-only reference material combining four well-characterized research peptides — GHK-Cu (copper tripeptide-1), BPC-157 (a gastric-derived pentadecapeptide), TB-500 (an N-acetylated thymosin beta-4 fragment, Ac-LKKTETQ), and KPV (an alpha-MSH-derived tripeptide). As a blend it has no single CAS number, molecular formula, or molecular weight; each component is identified by its own analytical identity. The catalog strength refers to 80 mg total peptide content. It is supplied as a lyophilized powder for in-vitro and analytical research applications only and is not for human or animal use.
Component identities
The blend comprises four research peptides characterized separately in the chemical literature. GHK-Cu: glycyl-L-histidyl-L-lysine coordinated to copper(II), commonly referenced under CAS 49557-75-7, with a reported ~340 g/mol mass for the 1:1 tripeptide-copper complex. BPC-157: the linear pentadecapeptide Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, PubChem CID 9941957, molecular formula C62H98N16O22, ~1419.6 g/mol, CAS 137525-51-0. TB-500: the N-acetylated heptapeptide Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ) corresponding to residues 17-23 of thymosin beta-4, PubChem CID 62707662, molecular formula C38H68N10O14, ~889.0 g/mol, CAS 885340-08-9. KPV: the tripeptide L-lysyl-L-prolyl-L-valine corresponding to the C-terminal 11-13 fragment of alpha-melanocyte-stimulating hormone, PubChem CID 125672, molecular formula C16H30N4O4, ~342.4 g/mol, CAS 67727-97-3.
Mechanism themes discussed in the literature
Each component is associated with distinct molecular-interaction themes in the research literature. GHK-Cu is studied for copper-ion coordination and tripeptide-metal complex chemistry. BPC-157 appears in studies of gastric-derived peptide stability and extracellular-matrix and cytoprotection-associated pathways. TB-500 (Ac-LKKTETQ) carries the actin-binding motif of thymosin beta-4 and is discussed in the context of cytoskeletal sequestration and cell-migration signaling. KPV, an alpha-MSH-derived tripeptide, is examined for melanocortin-pathway and inflammatory-signaling modulation in cell-based assays. The blend is intended for in-vitro investigation of these overlapping pathways within one sample.
| Full name | KLOW Blend (GHK-Cu / BPC-157 / TB-500 / KPV multi-peptide research blend) |
| Research theme | Cytoprotection blend |
| CAS number | |
| Molecular formula | |
| Molecular weight | |
| Purity | ≥98% (HPLC) |
| Physical form | Lyophilized powder |
| Storage | −20 °C, desiccated, protected from light |
Sequence
Reported research areas
- In-vitro cell-signaling and pathway studies
- Peptide analytical characterization and HPLC identity
- Comparative multi-peptide reference standards
- Receptor- and matrix-interaction literature reviews
Credible sources
- PubChem — GHK-Cu (copper tripeptide-1)
- PubChem — BPC-157 (CID 9941957)
- PubMed — thymosin beta-4 fragment / KPV peptide literature
COA with every lot
Each KLOW Blend lot is characterized by reversed-phase HPLC for purity and by mass spectrometry for identity, then documented in a per-lot Certificate of Analysis. Unique lot numbers tie the vial back to its synthesis batch and analytical data.
- RP-HPLC purity result (≥98% (HPLC))
- Mass-spectrometry identity confirmation
- Appearance, molecular weight, and storage
- Lot number and testing status
Specimen Certificate of Analysis
| Product | KLOW Blend (reference) |
| Lot | HXR-2406-104 |
| Purity (RP-HPLC) | 98%+ |
| Identity (MS) | Confirmed · |
| Appearance | Lyophilized powder |
| Storage | −20 °C, desiccated |
Representative document. Each lot has its own COA — these are quality documents, not medical claims.